Treatment of Non-Tuberculous Mycobacteria in Adults with Cystic Fibrosis

Non-tuberculous mycobacteria in cystic fibrosis.

BACKGROUND The clinical significance of the presence of non-tuberculous mycobacteria in the sputum of patients with cystic fibrosis is unclear. A retrospective case-control study was performed to assess possible risk factors for non-tuberculous mycobacteria and its impact on clinical status in patients with cystic fibrosis. METHODS The records of all patients attending the Leeds cystic fibros...

Infection by Non Tuberculous Mycobacteria in Cystic Fibrosis

Cystic fibrosis (CF) is a common autosomal recessive genetic condition affecting white population with an approximate incidence of 1 per 2500 live births (Davis et al., 1996), nearly 30,000 people in the USA (Olivier et al., 2003). Patients with this life-shortening disease have abnormally thickened secretions that facilitate chronic infection of the airways, bronchiectasis and early death. The...

CYSTIC FIBROSIS Non-tuberculous mycobacteria in end stage cystic fibrosis: implications for lung transplantation

Background: WC and NS contributed equally. Non-tuberculous mycobacteria (NTM) frequently colonise patients with end stage cystic fibrosis (CF), but its impact on the course of the disease following lung transplantation is unknown. Methods: Lung transplant recipients with CF who underwent lung transplantation at our institution between January 1990 and May 2003 (n = 146) and CF patients awaiting...

Comparing the Non-Cystic Fibrosis Bronchiectasis Patients with Non-Tuberculous Mycobacteria (NTM) and Non-NTM Infections

Nontuberculous mycobacteria in cystic fibrosis and non-cystic fibrosis bronchiectasis.

Increasing numbers of cystic fibrosis (CF) and non-CF bronchiectasis patients are affected by pulmonary nontuberculous mycobacteria (NTM) infection worldwide. Two species of NTM account for up to 95% of the pulmonary NTM infections: Mycobacterium avium complex (MAC) and Mycobacterium abscessus complex (MABSC). Diagnosis of pulmonary NTM infection is based on criteria specified in the 2007 Ameri...